A practical implementation guide that sets out a simple, evidence-based framework to help countries initiate or strengthen suicide prevention efforts. It focuses on four key interventions—such as limiting access to means, promoting responsible media reporting, building life skills in young people, and improving early identification and care—supported by cross-cutting pillars like governance, collaboration, and monitoring. Designed for both national and local stakeholders, the guide provides a structured starting point for developing coordinated, multi-sector suicide prevention strategies that can be adapted to different contexts.